產品屬性：
產品名稱 | (-)-Caryophyllene oxide |
規格 | 100mg、1g |
貨號 | EY-01Y10941 |
Cas No.: 1139-30-6
別名: N/A
化學名: N/A
分子式: C15H24O
分子量: 220.4
溶解度: DMF: 20 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
(-)-Caryophyllene oxide is a bicyclic sesquiterpene and a metabolite of β-caryophyllene that has been found in C. sativa and has anticancer properties. Unlike β-caryophyllene, (-)-caryophyllene oxide does not bind to the cannabinoid (CB) receptor CB2 (Ki = >20 μM). It induces calcium currents in HL-60 cells expressing CB2 receptors but also does so in CB2-deficient cells. (-)-Caryophyllene oxide is cytotoxic to HepG2, AGS, HeLa, SNU-1 and SNU-16 cells (IC50s = 3.95, 12.6, 13.55, 16.79, and 27.39 μM, respectively). It is the volatile component of C. sativa sensed by narcotic detection dogs. Formulations containing (-)-caryophyllene have been used as flavoring agents.
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